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arbocyanine(DiOC18(3)).Additionally,largeunilamellarvesicles(LUVs)functionedasadrugcarriersystem,incorporatingthespectrallydistinctfluorescentsulforhodamine101(SRh101)asasurrogatedrug.TheinvestigationemphasizedthediverseinteractionsbetweenGUVsandLUVsbasedonthechargedlipidsemployed.Weexaminedtheexchangekineticsandstructuralalterationsofliposomecarriersduringtheuptakeprocess.Ourstudyunderscoresthesignificanceofemploying2PexcitationinconjunctionwithFLIMandFCS.Thispowerfulcombinationoffersavaluablemethodologicalapproachforstudyingliposomeinteractions,positioningthemasanexceptionallyversatilemodelsystemwithadistincttechnicaladvante.FullarticleattachmentSupplementarymaterial:SupplementaryFile1(ZIP,1927KiB)11pes,535KiB OpenAccessCommunicationAProof-of-ConceptProteinMicroarray-BasedApproachforSerotypingofSalmonellaentericaStrainsbySaschaD.Braun,ElkeMüller,KatrinFrankenfeld,DominikGary,StefanMoneckeandRalfEhrichtPathogens2024,13(5),355;doi.org/10.3390/pathogens(registering DOI)-25Apr2024AbstractSalmonellaenterica,abacteriumcausingfoodborneillnesseslikesalmonellosis,isprevalentinEuropeandglobally.Itisfoundinfood,water,andsoil,leadingtosymptomslikediarrheaandfever.Annually,itresultsinabout95millioncasesworldwide,withincreasingantibiotic[...]Readmore.Salmonellaenterica,abacteriumcausingfoodborneillnesseslikesalmonellosis,isprevalentinEuropeandglobally.Itisfoundinfood,water,andsoil,leadingtosymptomslikediarrheaandfever.Annually,itresultsinabout95millioncasesworldwide,withincreasingantibioticresistanceposingapublichealthchallenge.Therefore,itisnecessarytodetectandserotypeSalmonellaforseveralreasons.TheidentificationoftheserovarsofSalmonellaentericaisolatesiscrucialtodetectandtraceoutbreaksandtoimplementeffectivecontrolmeasures.Ourworkpresentsaprotein-basedmicroarrayfortherapidandaccuratedeterminationofSalmonellaserovars.ThemicroarraycarriesasetofantibodiesthatcandetectdifferentSalmonellaO-andH-antigens,allowingfortheidentificationofmultipleserovars,includingTyphimuriumandEnteritidis,inasingleminiaturizedassay.Thesystemisfast,economical,accurate,andrequiresonlysmallsamplevolumes.Also,itisnotrequiredtomaintainanextensivecollectionofserafortheserotypingofSalmonella entericaserovarsandcanbeeasilyexpandedandadaptedtonewserovarsandsera.ThescientificstateoftheartinSalmonellaserotypinginvolvesthecomparisonoftraditional,molecular,andinsilicomethods,withafocusoneconomy,multiplexing,accuracy,rapidity,andadaptabilitytonewserovarsandsera.Thedevelopmentofprotein-basedmicroarrays,suchastheonepresentedinourwork,contributestotheongoingadvancementsinthisfield.Fullarticle(ThisarticlebelongstotheSpecialIssueNewApproachestoCombatingMultidrug-ResistantPathogens)attachmentSupplementarymaterial:SupplementaryFile1(ZIP,447KiB)21pes,1247KiB OpenAccessArticlePatternsofHumanMilkOligosaccharidesinMatureMilkAreAssociatedwithCertainGutMicrobiotainInfantsbyShuaiMao,AiZhao,HuaJiang,JingyuYan,WuxianZhong,YipingXunandYumeiZhangNutrients2024,16(9),1287;doi.org/10.3390/nu(registering DOI)-25Apr2024AbstractHumanmilkoligosaccharides(HMOs)arecomplexesthatplayacrucialroleinshapingtheearly-lifegutmicrobiota.ThisstudyintendstoexplorewhetherHMOpatternsareassociatedwiththegutmicrobiotaofinfants.Weincluded96Chinesebreastfeedingmother–infantdyads.Breastmilkand[...]Readmore.Humanmilkoligosaccharides(HMOs)arecomplexesthatplayacrucialroleinshapingtheearly-lifegutmicrobiota.ThisstudyintendstoexplorewhetherHMOpatternsareassociatedwiththegutmicrobiotaofinfants.Weincluded96Chinesebreastfeedingmother–infantdyads.Breastmilkandinfantfaecalsampleswerecollectedandtested.Withmilk2′-fucosyllactose,difucosyllactose,andlacto-N-fucopentaose-Iasbiomarkers,wedividedthemothersintosecretorandnon-secretorgroups.HMOpatternswereextractedusingprincipalcomponentanalysis.Themajority(70.7%)ofmotherswerecategorisedassecretorandfivedifferentHMOpatternswereidentified.Afteradjustment,theinfantsofsecretormothersexhibitedalowerrelativeabundanceofBifidobacteriumbifidum(β=−0.245,95%CI:−0.465~−0.025).AnHMOpatterncharacterisedbyhighlevelsof3-fucosyllactose,lacto-N-fucopentaose-III,andlacto-N-neodifucohexaose-IIwaspositivelyassociatedwiththerelativeabundanceofBifidobacteriumbreve(p=0.014),whilethepatterncharacterisedbylacto-N-neotetraose,6′-sialyllactose,andsialyllacto-N-tetraose-bwasnegativelyassociatedwithBifidobacteriumbreve(p=0.027).Thepatterncharacterisedbyhighlevelsofmonofucosyl-lacto-N-hexaose-IIIandmonofucosyl-lacto-N-neohexaosewaspositivelyassociatedwithBifidobacteriumdentium(p=0.025)andBifidobacteriumbifidum(p<0.001),respectively.ThisstudysuggeststhatHMOpatternsfrommaturebreastmilkwereassociatedwithcertaingutmicrobiotaofbreastfedinfants.Fullarticle(ThisarticlebelongstotheSpecialIssueRolesofDairyIntakeinHealthDevelopment)attachmentSupplementarymaterial:SupplementaryFile1(ZIP,415KiB)7pes,2331KiB OpenAccessCaseReportHepaticEpithelioidHemangioendotheliomainaDogbyLuisaVeraMuscatello,FedericoMassari,PaolaRoccabianca,GiuseppeSarli,CinziaBenazziandMarcoLuigiBianchiAnimals2024,14(9),1302;doi.org/10.3390/ani(registering DOI)-25Apr2024AbstractA5-year-oldspayedfemaleBretondogwasreferredforathyroidnodule.AtotalbodyCTscanevidencedmultifocalhepaticnodules.Cytologicalliversampleswerehemodilutedandnon-dinostic.Followingathyroidectomy,thehistologywasconsistentwithafollicular-compactthyroidcarcinoma.Onlaparoscopy,most[...]Readmore.A5-year-oldspayedfemaleBretondogwasreferredforathyroidnodule.AtotalbodyCTscanevidencedmultifocalhepaticnodules.Cytologicalliversampleswerehemodilutedandnon-dinostic.Followingathyroidectomy,thehistologywasconsistentwithafollicular-compactthyroidcarcinoma.Onlaparoscopy,mosthepaticlobeshadmultifocaldark-rednodulesthatwerebiopsiedforhistology.Microscopically,thehepaticparenchymainthenoduleswassubstitutedbybloodchannelslinedbyblandspindlecellsbutadjacenttoepithelioidneoplasticcells,singleorinclusters,embeddedinamoderateamountofedematouscollenmatrix.Thesecellshadopticallyemptycytoplasmicspace,occasionallycontainingerythrocytes(microlumina).Spindleandepithelioidcellsexpressedmembranous-to-cytoplasmicCD31andFVIII-RAconsistentwithendothelialorigin.Basedonmorphologyandimmunolabelling,ahemangioendotheliomawithepithelioiddifferentiationwasdinosed.Lesionsintheliverwereinitiallystable,showingprogressionwithtime.Thedogwasalivewithnosystemicclinicalsigns36monthsafterlaparoscopy.Fullarticle(ThisarticlebelongstotheSectionVeterinaryClinicalStudies)attachmentSupplementarymaterial:SupplementaryFile1(ZIP,638KiB)67pes,1965KiB OpenAccessReviewACriticalReviewoftheModellingToolsfortheReactiveTransportofOrganicContaminantsbyKatarzynaSamborska-GoikandMartaPogrzebaAppl.Sci.2024,14(9),3675;doi.org/10.3390/app(registering DOI)-25Apr2024AbstractThepollutionofgroundwaterandsoilbyhydrocarbonsisasignificantandgrowingglobalproblem.Effortstomitigateandminimisepollutionrisksareoftenbasedonmodelling.Modelling-basedsolutionsforpredictionandcontrolplayacriticalroleinpreservingdwindlingwaterresourcesand[...]Readmore.Thepollutionofgroundwaterandsoilbyhydrocarbonsisasignificantandgrowingglobalproblem.Effortstomitigateandminimisepollutionrisksareoftenbasedonmodelling.Modelling-basedsolutionsforpredictionandcontrolplayacriticalroleinpreservingdwindlingwaterresourcesandfacilitatingremediation.Theobjectivesofthisarticleareto:(i)toprovideaconciseoverviewofthemechanismsthatinfluencethemigrationofhydrocarbonsingroundwaterandtoimprovetheunderstandingoftheprocessesthataffectcontaminationlevels,(ii)tocompilethemostcommonlyusedmodelstosimulatethemigrationandfateofhydrocarbonsinthesubsurface;and(iii)toevaluatethesesolutionsintermsoftheirfunctionality,limitations,andrequirements.Theaimofthisarticleistoenablepotentialuserstomakeaninformeddecisionregardingthemodellingapproaches(deterministic,stochastic,andhybrid)andtomatchtheirexpectationswiththecharacteristicsofthemodels.Thereviewof111Dscreeningmodels,18deterministicmodels,7stochastictools,andmachinelearningexperimentsaimedatmodellinghydrocarbonmigrationinthesubsurfaceshouldprovideasolidbasisforunderstandingthecapabilitiesofeachmethodandtheirpotentialapplications.Fullarticle(ThisarticlebelongstotheSpecialIssueEnvironmentalBioaccumulationandAssessmentofToxicElements)attachmentSupplementarymaterial:SupplementaryFile1(ZIP,483KiB)17pes,2814KiB OpenAccessArticlePotentialRoleofCirculatingPD-L1+LeukocytesasaPredictorofResponsetoAnti-PD-(L)1TherapyinNSCLCPatientsbyGeorgiaAnguera,MariaMulet,CarlosZamora,RubénOsuna-Gómez,AndrésBarba,IvanaSullivan,JorginaSerra-López,ElisabetCantó,SilviaVidalandMargaritaMajemBiomedicines2024,12(5),958;doi.org/10.3390/biomedicines(registering DOI)-25Apr2024AbstractPD-(L)1inhibitorsarepartofthetreatmentstrategyfornon-smallcelllungcancer(NSCLC)althoughitsefficacyislimitedtocertainpatients.Ourstudyaimedtoidentifypatientswhomightbenefitfromanti-PD-(L)1inhibitorsbyanalyzingthePD-L1expressiononcirculatingleukocytesand[...]Readmore.PD-(L)1inhibitorsarepartofthetreatmentstrategyfornon-smallcelllungcancer(NSCLC)althoughitsefficacyislimitedtocertainpatients.Ourstudyaimedtoidentifypatientswhomightbenefitfromanti-PD-(L)1inhibitorsbyanalyzingthePD-L1expressiononcirculatingleukocytesanditsevolutionduringtreatment.OnehundredthirteenNSCLCpatients,accordingtotheirradiologicalresponseafter10–12weeksoftreatment,wereclassifiedintoresponders,stable,andprogressivedisease.PercentesofcirculatingPD-L1+leukocytes,PD-L1+platelets(PLTs),andleukocyte-PLTcomplexeswereassessedusingflowcytometry,andplasmaconcentrationsofsolubleimmunomodulatoryfactorswerequantifiedbyELISA.Respondersexhibitedsignificantlyhigherpre-treatmentpercentesofPD-L1+neutrophils,PD-L1+CD14+cells,andPD-L1+PLTsthanprogressors.Thepercentesofthesepopulationsdecreasedinresponderspost-treatment,contrastingwithstablesandprogressors.PLTsnotablycontributedtoPD-L1expressioninCD14+cellsandneutrophils.PlasmacytokineanalysisrevealedbaselinedifferencesonlyinIL-17concentrationamonggroups,whereasnetworkanalyseshighlighteddistinctassociationpatternsbetweenplasmamoleculesandPD-L1+leukocytesafter10–12weeksoftreatment.Ourfindingssuggestthatpre-treatmentassessmentofcirculatingPD-L1+neutrophils,PD-L1+CD14+cells,andPD-L1+PLTsmaybehelpfulinidentifyingNSCLCpatientswhoarepotentialcandidatesforanti-PD-(L)1therapy.Fullarticle(ThisarticlebelongstotheSpecialIssuePD-1/PD-L1andImmunotherapy)9658;9660;ShowFiguresFigure1Figure2---Figure3---Figure4---Figure5---Figure625pes,1114KiB OpenAccessArticleTextMiningandMulti-AttributeDecision-Making-BasedCourseImprovementinMassiveOpenOnlineCoursesbyPeiYang,YingLiu,YuyanLuo,ZhongWangandXiaoliCaiAppl.Sci.2024,14(9),3654;doi.org/10.3390/app(registering DOI)-25Apr2024AbstractAstheleadingplatformofonlineeducation,MOOCsprovidelearnerswithrichcourseresources,butcoursedesignersarestillfacedwiththechallengeofhowtoaccuratelyimprovethequalityofcourses.Currentresearchmainlyfocusesonlearners’emotionalfeedbackondifferentcourse[...]Readmore.Astheleadingplatformofonlineeducation,MOOCsprovidelearnerswithrichcourseresources,butcoursedesignersarestillfacedwiththechallengeofhowtoaccuratelyimprovethequalityofcourses.Currentresearchmainlyfocusesonlearners’emotionalfeedbackondifferentcourseattributes,neglectingnon-emotionalcontentaswellasthecostsrequiredtoimprovetheseattributes.Thislimitationmakesitdifficultforcoursedesignerstofullygrasptherealneedsoflearnersandtoaccuratelylocatethekeyissuesinthecourse.Toovercometheabovechallenges,thisstudyproposesanMOOCimprovementmethodbasedontextminingandmulti-attributedecision-making.Firstly,weutilizewordvectorsandclusteringtechniquestoextractcourseattributesthatlearnersfocusonfromtheircomments.Secondly,withthehelpofsomedeeplearningmethodsbasedonBERT,weconductasentimentanalysisonthesecommentstoreveallearners’emotionaltendenciesandnon-emotionalcontenttowardscourseattributes.Finally,weadoptthemulti-attributedecision-makingmethodTOPSIStocomprehensivelyconsidertheemotionalscore,attention,non-emotionalcontent,andimprovementcostsoftheattributes,providingcoursedesignerswithapriorityrankingforattributeimprovement.WeappliedthismethodtotwotypicalMOOCprogrammingcourses—ClangueandJalangue.Theexperimentalfindingsdemonstratethatourapproacheffectivelyidentifiescourseattributesfromreviews,assesseslearners’satisfaction,attention,andcostofimprovement,andultimatelygeneratesaprioritizedlistofcourseattributesforimprovement.Thisstudyprovidesanewapproachforimprovingthequalityofonlinecoursesandcontributestothesustainabledevelopmentofonlinecoursequality.Fullarticle(ThisarticlebelongstotheSpecialIssueApplicationofArtificialIntelligenceMethodsinProcessingofEmotions,DecisionsandOpinions)13pes,768KiB OpenAccessReviewriculturalDisasterPreventionSystem:InsightsfromTaiwan’sAdaptationStrategiesbyMing-HwiYao,Yung-HengHsu,Ting-YiLi,Yung-MingChen,Chun-TangLu,Chi-LingChenandPei-YuShihAtmosphere2024,15(5),526;doi.org/10.3390/atmos(registering DOI)-25Apr2024AbstractInresponsetotheadverseeffectsofclimatechange-inPlease Wait... | Cloudflareducedfrequentextremedisastersonriculturalproductionandsupplystability,thisstudydevelopsacomprehensivericulturaldisasterpreventionsystembasedoncurrentadaptationstrategiesformitigatingriculturalmeteorologicaldisasters.Theprimarygoalistoenhance[...]Readmore.Inresponsetotheadverseeffectsofclimatechange-inducedfrequentextremedisastersonriculturalproductionandsupplystability,thisstudydevelopsacomprehensivericulturaldisasterpreventionsystembasedoncurrentadaptationstrategiesformitigatingriculturalmeteorologicaldisasters.Theprimarygoalistoenhancedisasterpreparednessandrecoverythroughthreecoreplatforms:afine-scaleweatherforecastservicesystem,acropdisasterearlywarningsystem,andanriculturalinformationserviceplatformfordisasters.TheresultsshowthateverymajorriculturalproductiontownshipinTaiwannowhasdedicatedriculturalweatherstationsandaccesstorefinedweatherforecasts.Additionally,adisasterpreventioncalendarfor76importantcropsisestablished,integratingcultivationmanementpracticesandcriticaldisasterthresholdsfordifferentgrowthperiods.Utilizingthiscalendar,thecropdisasterearlywarningsystemcanprovidetimelydisaster-relatedinformationandpre-disasterpreventionassistancetofarmersthroughvariousinformationdisseminationtools.Asadisasterapproaches,thericulturalinformationserviceplatformfordisastersprovidesupdatesoncurrentcropgrowthconditions.Thisservicenotonlypinpointsareasathigherriskofdisastersandvulnerablecroptypesbutalsooffersmitigationsuggestionstopreventpotentialdame.Administrativeefficiencyisthenimprovedwitharesponsemechanismincorporatingdronesandimeanalysisforearlydisasterdetectionandrapidresponse.Insummary,thecollaborativeeffortsoutlinedinthisstudydemonstrateaproactiveapproachtoriculturaldisasterprevention.Byleveringtechnologicaladvancementsandinterdisciplinarycooperation,theaimistosafeguardriculturallivelihoodsandensurefoodsecurityinthefaceofclimate-inducedchallenges.Fullarticle(ThisarticlebelongstotheSpecialIssuericulture-ClimateInteractionsinTropicalRegions)9pes,235KiB OpenAccessArticleTheBlow-UpoftheLocalEnergySolutiontotheWeEquationwithaNontrivialBoundaryConditionbyYulongLiuMathematics2024,12(9),1317;doi.org/10.3390/math(registering DOI)-25Apr2024AbstractInthisstudy,weexaminetheweequationwithanontrivialboundarycondition.Themaintargetofthisstudyistoprovethelocal-in-timeexistenceandtheblow-upinfinitetimeoftheenergysolution.Throughtheconstructionofanauxiliaryfunctionand[...]Readmore.Inthisstudy,weexaminetheweequationwithanontrivialboundarycondition.Themaintargetofthisstudyistoprovethelocal-in-timeexistenceandtheblow-upinfinitetimeoftheenergysolution.Throughtheconstructionofanauxiliaryfunctionandtheimpositionofappropriateconditionsontheinitialdata,weestablishthebothlowerandupperboundsfortheblow-uptimeofthesolution.Meanwhile,basedontheseestimates,weobtaintheresultofthelocal-in-timeexistenceandtheblow-upoftheenergysolution.Thisapproachenhancesourunderstandingofthedynamicsleadingtoblow-upintheconsideredcondition.Fullarticle(ThisarticlebelongstotheSpecialIssueAdvancesinDifferentialandDifferenceEquationsandTheirApplications)19pes,2965KiB OpenAccessArticleStructural,OpticalandDielectricPropertiesofSomeNanocompositesDerivedfromCopperOxideNanoparticlesEmbeddedinPoly(vinylpyrrolidone)MatrixbyCarmenGherasim,MihaiAsandulesa,NicusorFifere,FloricaDoroftei,DanielTîmpuandAntonAirineiNanomaterials2024,14(9),759;doi.org/10.3390/nano(registering DOI)-25Apr2024AbstractPolymernanocompositefilmsbasedonpoly(vinylpyrrolidone)incorporatedwithdifferentamountsofcopperoxide(CuO)nanoparticleswerepreparedbythesolutioncastingtechnique.ThePVP/CuOnanocompositeswereanalyzedbyX-raydiffractometry(XRD),scanningelectronmicroscopy,UV–Visibleabsorptionspectroscopyanddielectricspectroscopy.TheXRD[...]Readmore.Polymernanocompositefilmsbasedonpoly(vinylpyrrolidone)incorporatedwithdifferentamountsofcopperoxide(CuO)nanoparticleswerepreparedbythesolutioncastingtechnique.ThePVP/CuOnanocompositeswereanalyzedbyX-raydiffractometry(XRD),scanningelectronmicroscopy,UV–Visibleabsorptionspectroscopyanddielectricspectroscopy.TheXRDanalysisshowedthatthemonoclinicstructureofcupricoxidewasmaintainedinthePVPhostmatrix.Thekeyopticalparameters,suchasopticalenergygapEg,UrbachenergyEU,absorptioncoefficientandrefractiveindex,wereestimatedbasedontheUV-Visdata.TheopticalcharacteristicsofthenanocompositefilmsrevealedthattheirtransmittanceandabsorptionwereinfluencedbytheadditionofCuOnanoparticlesinthePVPmatrix.IncorporationofCuOnanoparticlesintothePVPmatrixledtoasignificantdecreaseinbandgapenergyandanincreaseintherefractiveindex.ThedielectricandelectricalbehiorsofthePVP/CuOnanocompositeswereanalyzedoverafrequencyrangebetween10Hzand1MHz.TheeffectofCuOloadingonthedielectricparameters(dielectricconstantanddielectricloss)ofthemetaloxidenanocompositeswasalsodiscussed.Fullarticle12pes,512KiB OpenAccessArticleTheCurrentAchievementsofMulti-GenePanelTestsinClinicalSettingsforPatientswithNon-Small-CellLungCancerbyTadashiSakuchi,AkemiIketani,SeiyaEsumi,MakiEsumi,YutaSuzuki,KentaroIto,KentaroFujiwara,YoichiNishii,KojiKatsuta,HirokiYasui,OsamuTuchiandOsamuHatajiCancers2024,16(9),1670;doi.org/10.3390/cancers(registering DOI)-25Apr2024AbstractSomemulti-genepaneltestshebeenimplementedinclinicalsettingstoguidetargetedtherapyinnon-small-celllungcancer(NSCLC)inJapan.Thecurrentperformanceofmulti-genepaneltestsundertheconditionthattheOncomineDxTargetTest(ODxTT)andAmoyDx®Pan[...]Readmore.Somemulti-genepaneltestshebeenimplementedinclinicalsettingstoguidetargetedtherapyinnon-small-celllungcancer(NSCLC)inJapan.Thecurrentperformanceofmulti-genepaneltestsundertheconditionthattheOncomineDxTargetTest(ODxTT)andAmoyDx®PanLungCancerPCRpanel(AmoyDx-multi)areailableremainsrelativelyunknown.WeretrospectivelyreviewedconsecutivepatientswithNSCLC,whoseFFPEsampleswereconsideredforgenetictesting.Weassessedthesubmissionrates,thesuccessrates,andthedriveroncogenedetectionratesofmulti-genepaneltests.Atotalof225patientswerehistologicallynewlydinosedwithNSCLCordinosedwitharecurrenceofNSCLCwithoutapreviousmulti-genepaneltestatourinstitution.Amongthe225patients,theFFPEsamplesof212patients(94.2%)weresubmittedformulti-genepaneltesting,including191samples(84.9%)fortheODxTTand21samples(9.3%)fortheAmoyDx-multi.Amongthe212samplessubmittedtomulti-genepaneltests,thesuccessratewas99.5%(211/212).Thedetectionrateofdriveroncogenealterationsforallhistologieswas52.4%(111/212),andthatforadenocarcinomawas69.7%(106/152).Aforablesubmissionrateandsuccessrateofmulti-genepaneltestswereshown,alongwithaforabledetectionrateinrecentclinicalsettings.Fullarticle(ThisarticlebelongstotheSectionCancerBiomarkers)attachmentSupplementarymaterial:SupplementaryFile1(ZIP,131KiB)21pes,KiB OpenAccessArticleGC-IMS-BasedVolatileCharacteristicAnalysisofHypsizygusmarmoreusDriedbyDifferentMethodsbyPufuLai,LongxiangLi,YingyingWei,JunzhengSun,BaoshaTang,YanrongYang,JunchenChenandLiWuFoods2024,13(9),1322;doi.org/10.3390/foods(registering DOI)-25Apr2024AbstractGaschromatography–ionmobilityspectroscopy(GC-IMS)wasusedtoanalyzethevolatilecomponentsindriedHypsizygusmarmoreusofdifferentdryingmethods,includinghPlease 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Cloudflareotairdrying(HAD),heatpumpdrying(HPD),heatedfreeze-drying(HFD),andunheatedfreeze-drying(UFD).Atotalof116signalpeakscorresponding[...]Readmore.Gaschromatography–ionmobilityspectroscopy(GC-IMS)wasusedtoanalyzethevolatilecomponentsindriedHypsizygusmarmoreusofdifferentdryingmethods,includinghotairdrying(HAD),heatpumpdrying(HPD),heatedfreeze-drying(HFD),andunheatedfreeze-drying(UFD).Atotalof116signalpeakscorrespondingto96volatilecompoundswereidentified,including25esters,24aldehydes,23alcohols,13ketones,10heterocycliccompounds,8carboxylicacids,7terpenes,3sulfur-containingcompounds,2nitrogen-containingcompounds,and1aromatichydrocarbon.ThetotalcontentofvolatilecompoundsinH.marmoreusdriedbythefourmethods,fromhighesttolowest,wasasfollows:HAD,HPD,HFD,andUFD.Themainvolatilecompoundsincludedcarboxylicacids,alcohols,esters,andaldehydes.ComparingthepeakintensitiesofvolatilecompoundsindriedH.marmoreususingdifferentdryingmethods,itwasfoundthatthesynthesisofesters,aldehydes,andterpenesincreasedunderhotdryingmethodssuchasHADandHPD,whilethesynthesisofcompoundscontainingsulfurandnitrogenincreasedunderfreeze-dryingmethodssuchasHFDandUFD.NinecommonkeycharacteristicflorcompoundsofdriedH.marmoreuswerescreenedusingrelativeodoractivityvalues(RO>1),includingethyl3-methylbutanoate,aceticacid,2-methylbutanal,propanal,methyl2-propenylsulfate,trimethylamine,3-octanone,acetaldehide,andthiophene.IntheodordescriptionofvolatilecompoundswithRO>0.1,itwasfoundthatimportantflorcomponentssuchastrimethylamine,3-octanone,(E)-2-octenal,anddimethyldisulfidearerelatedtothearomaofseafood.TheirROorderisHFD>UFD>HPD>HAD,indicatingthatH.marmoreususingtheHFDmethodhethestrongestseafoodflor.TheresearchfindingsprovidetheoreticalguidanceforselectingdryingmethodsandrefiningtheprocessingofH.marmoreus.Fullarticle(ThisarticlebelongstotheSectionFoodAnalyticalMethods)9658;9660;ShowFiguresGraphicalabstractFigure1---Figure2---Figure3---Figure4---Figure5---Figure6---Figure7---Figure820pes,3897KiB OpenAccessArticleMeshlessGeneralizedFiniteDifferenceMethodBasedonNonlocalDifferentialOperatorsforNumericalSimulationofElastostaticsbyYeyingZhou,ChunguangLi,XinshanZhuangandZhifenWangMathematics2024,12(9),1316;doi.org/10.3390/math(registering DOI)-25Apr2024AbstractThisstudyproposesaninnovativemeshlessapproachthatmergestheperidynamicdifferentialoperator(PDDO)withthegeneralizedfinitedifferencemethod(GFDM).BasedonthePDDOtheory,thismethodintroducesanewnonlocaldifferentialoperatorthataimstoreducethepre-assumptionrequiredforthe[...]Readmore.Thisstudyproposesaninnovativemeshlessapproachthatmergestheperidynamicdifferentialoperator(PDDO)withthegeneralizedfinitedifferencemethod(GFDM).BasedonthePDDOtheory,thismethodintroducesanewnonlocaldifferentialoperatorthataimstoreducethepre-assumptionrequiredforthePDDOmethodandsimplifythecalculationprocess.Bydiscretizingthroughtheparticleapproximationmethod,thistechniqueproficientlypreservesthePDDO’snonlocalfeatures,enhancingthenumericalsimulation’sflexibilityandusability.Throughthenumericalsimulationofclassicalelasticstaticproblems,thisarticlefocusesontheevaluationofthecalculationaccuracy,calculationefficiency,robustness,andconvergenceofthemethod.Thismethodissignificantlystrongerthanthefiniteelementmethodinmanyperformanceindicators.Infact,thisstudydemonstratesthepracticabilityandsuperiorityoftheproposedmethodinthefieldofelasticstaticsandprovidesanewapproachtomorecomplexproblems.Fullarticle(ThisarticlebelongstotheSpecialIssueRecentAdvancesinNumericalMethodsforScientificandEngineeringApplications,2ndEdition)12pes,KiB OpenAccessArticleHigh-BandwidthLumpedMach-ZehnderModulatorsBasedonThin-FilmLithiumNiobatebyPengYang,SiweiSun,YuqiangZhang,RuiCao,HuiminHe,HaiyunXueandFengmanLiuPhotonics2024,11(5),399;doi.org/10.3390/photonics(registering DOI)-25Apr2024AbstractRecently,lumpedMach-ZehnderModulators(MZMs)hereceivedrenewedattentionduetotheirpotentialforlowpowerconsumptionandcompactsize.However,thepracticalityoflumpedMZMswithconventionallumpedelectrodes(C-LEs)islimitedbytheirlowerelectro-optical(EO)bandwidth.ThereductioninEO[...]Readmore.Recently,lumpedMach-ZehnderModulators(MZMs)hereceivedrenewedattentionduetotheirpotentialforlowpowerconsumptionandcompactsize.However,thepracticalityoflumpedMZMswithconventionallumpedelectrodes(C-LEs)islimitedbytheirlowerelectro-optical(EO)bandwidth.ThereductioninEObandwidthresultsfromtheinherenttrade-offbetweenEObandwidthandhalf-wevoltelengthproduct(VπL)withintheC-LEarchitecture.Thispaperproposesathin-filmlithiumniobate(TFLN)-basedlumpedMZMwithcapacitively-loadedlumpedelectrodes(CL-LEs).ThepurelylinearEOeffectoftheLNeliminatestheparasiticcapacitanceinthedopedPNjunctionandenhancestheEObandwidth.Furthermore,theCL-LEstructurecanbreakthelimitationbetweenEObandwidthandVπLinherentintheC-LEdesign.SimulationsshowtheproposeddeviceachievesahighEObandwidthof32.4GHzandalowVπLof1.15V·cm.DuetothereducedcapacitanceandlowerVπL,thepowerconsumptionofthedeviceisaslowas0.1pJ/bit.Simulationresultsindicatethattheopen-eyediramsareachievedat64Gb/sfor1.5mmTFLNlumpedMZM,withanERof2.97dB.Consequently,theproposeddevicearchitecturesubstantiallyenhancestheperformanceoflumpedMZMs,showingpromiseforapplicationinshort-reachopticalinterconnectswithindatacenters.Fullarticle(ThisarticlebelongstotheSectionOptoelectronicsandOpticalMaterials)21pes,1095KiB OpenAccessArticleOptimizingCropWaterProductivityinGreenhousePepperbySusanaZapata-García,AbdelmalekTemnani,PabloBerríos,PedroJ.Espinosa,ClaudiaMonllorandAlejandroPérez-Pastorronomy2024,14(5),902;doi.org/10.3390/ronomy(registering DOI)-25Apr2024AbstractAlthoughadvancedproductionsystemshebeendevelopedinthelast20years,waterscarcityisstillagrowingprobleminriculture.Thisstudyaimstoevaluatetheeffectofdifferentstrategiesthatcombinetheapplicationofseaweedandmicrobialbiostimulantswithregulateddeficit[...]Readmore.Althoughadvancedproductionsystemshebeendevelopedinthelast20years,waterscarcityisstillagrowingprobleminriculture.Thisstudyaimstoevaluatetheeffectofdifferentstrategiesthatcombinetheapplicationofseaweedandmicrobialbiostimulantswithregulateddeficitirrigation(RDI)strategiesontheirrigationwaterproductivity(WPI),fruitqualityparametersandsoilenzymaticactivityinpepperplants(Capsicumannumsp.)undertwocommercialgreenhouseconditions.Ineachtrial,twotreatmentswereapplied:(i)irrigationaccordingtoFarmercriteriawithoutbiostimulantapplicationsand(ii)acombinedtreatmentofRDIandthesamebiostimulationprogram,composedofBacillusparalicheniformisandAscophillumnodosumextracts.RDIwasappliedindifferentphenologicalstesineachgreenhouseaftertheestablishmentuntilthe1stharvestintrial1orduringtheripeningandharvestperiodintrial2.Onere,theirrigationwasreducedby600m3ha−1comparedtotheFarmerirrigationschedule.Inbothtrials,biostimulationpromotedanincreaseinfruitnumbers,punctuallyintrial1,leadingtoyieldprecocity,orgenerallyintrial2,obtainingahigheryield.Globally,WPIwasincreasedwhenRDIwascombinedwithbiostimulation.Thiscombinedtreatmentalsoenhancedtherootwaterabsorptionandimprovedthesoilenzymaticactivityinbothgreenhouses,suggestingthatnutrientsinthesoilwouldbecomemoreailabletoplants.Thus,thecombinedactionofbiostimulationunderdifferentRDIstrategieshasbeenprovedtobeausefulstrategytoimprovericulturalsustainability.Fullarticle(ThisarticlebelongstotheSpecialIssueAssessmentandMappingofSoilWaterBalance)16pes,3661KiB OpenAccessArticleCoupledProcessesatMicro-andMacroscopicLevelsforLong-TermPerformanceAssessmentStudiesofNuclearWasteRepositoriesbyHuaShao,EikeRadeisen,JürgenHesser,WenqingWangandOlafKolditzMinerals2024,14(5),453;doi.org/10.3390/min(registering DOI)-25Apr2024AbstractPerformanceassessmentofnuclearwasterepositoriesrequiresstate-of-the-artknowledgeofradionuclidetransportproperties.Additionally,theshort-termdevelopmentunderthermalpulsesandthelong-termdevelopmentofthenearfield—duetoinfluencessuchasgasgeneration—mustbeevaluated.Keythermal-hydro-mechanical-chemicalprocessesarestronglycoupledon[...]Readmore.Performanceassessmentofnuclearwasterepositoriesrequiresstate-of-the-artknowledgeofradionuclidetransportproperties.Additionally,theshort-termdevelopmentunderthermalpulsesandthelong-termdevelopmentofthenearfield—duetoinfluencessuchasgasgeneration—mustbeevaluated.Keythermal-hydro-mechanical-chemicalprocessesarestronglycoupledondifferentspatialandtemporalscales.Tounderstandthesecouplingmechanisms,numerousmaterialmodelsandnumericalcodeshebeendeveloped.However,theexistingconstitutiveapproaches—whichhebeenadaptedtodescribesmall-scalelaboratoryexperimentsandvalidatedainstreal-scalefieldobservations—areoftenunabletocapturelong-termmaterialbehiorwithsufficientprecision.Tobuildtheconfidence,amorecomprehensiveunderstandingofthesystematmicro-andmacroscopicscalesisrequired.Mostobservedmacroscopicprocessesresultfrommicroscopicchangesinthecrystalstructureand/orcrystallinegregates,aswellaschangesinmaterialpropertiesundertheinfluenceofvariousfactors.Tocharacterizethesephysicalfieldsincrystals,microscopicinvestigations,suchasvisualization,orgeophysicalmethodsareintroducedtoverifytheunderstandingatthemicroscale.Twocasesaredemonstratedforthepresentedconceptusingmicroscaleinformation:onedealswiththemechanicallyandthermallydrivenmigrationoffluidinclusionsinrocksalt,theotherwithdilatancy-controlledgastransportinwater-saturatedclaymaterial.Fullarticle(ThisarticlebelongstotheSpecialIssueImplicationsofTHMCProcessesonLong-TermSafetyofGeologicalDisposalofRadioactiveWaste)16pes,2003KiB OpenAccessArticleADeepLearningMethodforLogDiameterMeasurementUsingWoodImesBasedonYolov3andDeepLabv3+byZhenglanLu,HuiluYao,YubiaoLyu,ShengHe,HengNing,YuhuiYu,LixiaZhaiandLinZhouForests2024,15(5),755;doi.org/10.3390/f(registering DOI)-25Apr2024AbstractWoodvolumeisanimportantindicatorintimbertrading,andlogdiameterisoneoftheprimaryparametersusedtocalculatewoodvolume.Currently,themostcommonmethodsformeasuringlogdiametersaremanualmeasurementorvisualestimationbylogscalers,whichare[...]Readmore.Woodvolumeisanimportantindicatorintimbertrading,andlogdiameterisoneoftheprimaryparametersusedtocalculatewoodvolume.Currently,themostcommonmethodsformeasuringlogdiametersaremanualmeasurementorvisualestimationbylogscalers,whicharelaborious,timeconsuming,costly,anderrorproneowingtotheirregularplacementoflogsandlargenumbersofroots.Additionally,thisapproachcaneasilyleadtomisrepresentationofdataforprofit.Thisstudyproposesamodelforautomaticlogdiametermeasurementthatisbasedondeeplearningandusesimestoaddresstheexistingproblems.Thespecificmeasurestoimprovetheperformanceandaccuracyoflog-diameterdetectionareasfollows:(1)AdualnetworkmodelisconstructedcombiningtheYolov3algorithmandDeepLabv3+architecturetoadapttodifferentlog-endcolorstatesthatconsidersthecomplexityoflog-endfaces.(2)AprilTvisionlibraryisaddedtoestimatethecamerapositionduringimeacquisitiontoachievereal-timeadjustmentoftheshootingangleandreducetheeffectoflog-imedeformationontheresults.(3)ThebackbonenetworkisreplacedwithaMobileNetv2convolutionalneuralnetworktomigratethemodeltomobiledevices,whichreducesthenumberofnetworkparameterswhilemaintainingdetectionaccuracy.Thetrainingresultsshowthatthemeanereprecisionoflog-diameterdetectionreaches97.28%andthemeanintersectionoverunion(mIoU)oflogsegmentationreaches92.22%.Comparisonswithothermeasurementmodelsdemonstratethattheproposedmodelisaccurateandstableinmeasuringlogdiameterunderdifferentenvironmentsandlightingconditions,withanereaccuracyof96.26%.Intheforestrytest,themeasurementerrorsforthevolumeofanentiretruckloadoflogsandasinglelogdiameterare1.20%and0.73%,respectively,whicharelessthanthecorrespondingerrorrequirementsspecifiedintheindustrystandards.Theseresultsindicatethattheproposedmethodcanprovideaviableandcost-effectivesolutionformeasuringlogdiametersandofferingthepotentialtoimprovetheefficiencyoflogmeasurementandpromotefairtradepracticesinthelumberindustry.Fullarticle(ThisarticlebelongstotheSectionWoodScienceandForestProducts)attachmentSupplementarymaterial:SupplementaryFile1(ZIP,20KiB)13pes,2581KiB OpenAccessArticleDoInvasiveJor333;Spiders(Trichonephilaclata)fromAsiaoidEatingUnpalatableMonarchButterflies(Danausplexippus)inNorthAmerica?byAndrewK.Dis,WilsonTownsendMorris,EmmaHobbsandEllaBlakelyInsects2024,15(5),309;doi.org/10.3390/insects(registering DOI)-25Apr2024AbstractAninvasivespiderfromEastAsiahasestablishedintheU.S.southeast(the“jor333;spider,”Trichonephilaclata)andisrapidlyexpandingitsrange.Studiesassessingtheimpactofthisspeciesareneeded,includinghowexpansiveitsdietis.Anopenquestionis[...]Readmore.AninvasivespiderfromEastAsiahasestablishedintheU.S.southeast(the“jor333;spider,”Trichonephilaclata)andisrapidlyexpandingitsrange.Studiesassessingtheimpactofthisspeciesareneeded,includinghowexpansiveitsdietis.Anopenquestioniswhethermonarchbutterflies,Danausplexippus,areapotentialpreyitemforthisspider,giventhatjor333;spidersdonotcoexistwithmonarchsintheirnativerange.Sincemonarchlarvaefeedonmilkweed,theysequestercardiacglycosidesintotheiradulttissues,renderingthemunpalatabletomanypredators.AtsiteswithinnortheastGeorgia,westedaseriesoftrials(n=61)wherewetossedmonarchsintojor333;spiderwebsand,forcomparison,performedsimilartrialswithanotheraposematicspecies,gulffritillary(raulisvanilla),andapalatablespecies,tigerswallowtail(Papilioglaucus).Werecordedtheoutcomeofthetrials,whichincludedwhetherthespiderattackedordidnotattacktheprey.Wealsoconductedavisualsurveyduringthesamefallseasontolookforevidenceofjor333;spidersconsumingmonarchsnaturally.Ourfindingsrevealedthatjor333;spidersoidedeatingmonarchs;spidersonlyattackedmonarchs20%ofthetime,whichwassignificantlylessthantheattackratesofsimilarlysizedorlargerbutterflies:86%forgulffritillariesand58%fortigerswallowtails.Somejor333;spidersevenremovedmonarchsfromtheirwebs.Fromourvisualsurveysofthesurroundingarea,wefoundnoevidenceofnaturalmonarchconsumptionand,ingeneral,butterfliesmadeuponlyafractionofthejor333;spiderdiet.Weconcludethatjor333;spidersappeartorecognizemonarchbutterfliesasbeingunpalatable,evenwithouthingapriorhistorywiththespecies.Thisinvokesquestionsabouthowthesespiderscanimmediatelyrecognizetheirunpalatabilitywithouttouchingthebutterflies.Fullarticle(ThisarticlebelongstotheSectionOtherArthropodsandGeneralTopics)attachmentSupplementarymaterial:SupplementaryFile1(ZIP,102KiB)9pes,329KiB OpenAccessArticleTheRoleofPsychosomaticTraitsinTailoredWorkupforAnteriorCervicalDiscectomyandFusion—ACaseSeriesbyMarcoBattistelli,EdoardoMazzucchi,MarioMuselli,FilippoMariaPolli,GianlucaGalieri,PaolaBazzu,FabrizioPignotti,AlessandroOlivi,GiovanniSabatinoandGiuseppeLaRoccaJ.Pers.Med.2024,14(5),454;doi.org/10.3390/jpm(registering DOI)-25Apr2024AbstractStudydesign:Prospectivestudy.Objective:Toevaluatetheinfluenceofpreoperativelyassessedpsychosomatictraitsonpostoperativepain,disability,andqualityoflifeoutcomes.Summaryofbackgrounddata:Anteriorcervicaldiscectomyandfusion(ACDF)isawidelyemployedsurgicalprocedurefortreatingcervicalspondylosis.[...]Readmore.Studydesign:Prospectivestudy.Objective:Toevaluatetheinfluenceofpreoperativelyassessedpsychosomatictraitsonpostoperativepain,disability,andqualityoflifeoutcomes.Summaryofbackgrounddata:Anteriorcervicaldiscectomyandfusion(ACDF)isawidelyemployedsurgicalprocedurefortreatingcervicalspondylosis.Despiteitseffectiveness,variousstudieshereportednon-successratesintermsofalleviatingdisabilityandpain.Psychologicalfactorshebecomeincreasinglyrecognizedascriticaldeterminantsofsurgicaloutcomesinvariousmedicaldisciplines.ThefullextentoftheirimpactwithinthecontextofACDFremainsinsufficientlyexplored.Thiscaseseriesaimstoassesstheinfluenceofpreoperativepsychologicalprofilingonlong-termpain,disabilityandqualityoflifeoutcomes.Methods:Weconductedaprospectivecohortstudyofprospectivelycollecteddatafrom76consecutivepatientswhounderwentACDFwithPEEKinter-fixedcesfromJuly2019toNovember2021.ThepreoperativepsychologicaltraitswereassessedusingtheSymptomChecklist90(SCL-90)questionnaire.TheOswestryDisabilityIndex(ODI),VisualAnalogueScale(VAS),NeckDisabilityindex(NDI),EuroQol-5D(EQ-5D),andShortForm-36(SF-36)werecollectedpreoperatively,onemonthpostoperatively,andatleastoneyearafterthesurgicalprocedure.Results:Thecorrelationanalysesrevealedassociationsbetweenpsychosomatictraitsandmultiplepreoperativeandpostoperativeoutcomemeasures.TheunivariateanalysesandlinearregressionanalysesdemonstratedtheinfluenceoftheGlobalSeverityIndex(GSI)overthefinalfollow-upscoresfortheODI,VAS,NDI,EQ-5D,andSF-36.TheGSIconsistentlyexhibitedastrongercorrelationwiththefinalfollow-uppain,disability,andqualityoflifeoutcomeswithrespecttothecorrespondentpreoperativevalues.Conclusion:ThisstudyhighlightstheimportanceofpsychosomatictraitsaspredictivefactorsforACDFoutcomesandemphasizestheirrelevanceinpreoperativeassessmentforinformingpatientsaboutrealisticexpectations.Thefindingsunderscoretheneedtoconsiderpsychologicalprofilesinthepreoperativeworkup,openingenuesforresearchintomedicationsandpsychologicaltherapies.Recognizingtheinfluenceofpsychosocialelementsinformstreatmentstrategies,fosteringtailoredsurgicalapproachesandpatientcare.Fullarticle(ThisarticlebelongstotheSpecialIssuePrecisionMedicineinNeurosurgery)attachmentSupplementarymaterial:SupplementaryFile1(ZIP,1545KiB)18pes,6275KiB OpenAccessArticleTheInfluenceoftheMechanicalComplianceofaSubstrateontheMorphologyofNanoporousGoldThinFilmsbySadiShahriar,KyaSomayajula,ConnerWinkeljohn,JeremyK.MasonandErkinSekerNanomaterials2024,14(9),758;doi.org/10.3390/nano(registering DOI)-25Apr2024AbstractNanoporousgold(np-Au)hasfounditsuseinapplicationsrangingfromcatalysistobiosensing,whereporemorphologyplaysacriticalroleinperformance.Whilethemorphologyevolutionofbulknp-Auhasbeenwidelystudied,knowledgeaboutitsthin-filmformislimited.Thiswork[...]Readmore.Nanoporousgold(np-Au)hasfounditsuseinapplicationsrangingfromcatalysistobiosensing,whereporemorphologyplaysacriticalroleinperformance.Whilethemorphologyevolutionofbulknp-Auhasbeenwidelystudied,knowledgeaboutitsthin-filmformislimited.Thisworkhypothesizesthatthemechanicalcomplianceofthethinfilmsubstratecanplayacriticalroleinthemorphologyevolution.Viaexperimentalandfinite-element-analysisapproaches,weinvestigatethemorphologicalvariationinnp-Authinfilmsdepositedoncompliantsilicone(PDMS)substratesofarangeofthicknessesanchoredonrigidglasssupportsandcomparethosetothemorphologyofnp-Audepositedonglass.Moremacroscopic(10sto100sofmicrons)cracksanddiscreteislandsforminthenp-AufilmsonPDMScomparedtoonglass.Conversely,uniformlydistributedmicroscopic(100sofnanometers)cracksformingreaternumbersinthenp-AufilmsonglassthanthoseonPDMS,withthecrackslocatedwithinthediscreteislands.Thenp-Aufilmsonglassalsoshowlargerligamentandporesizes,possiblyduetohigherresidualstressescomparedtothenp-Au/PDMSfilms.TheeffectiveelasticmodulusofthesubstratelayersdecreaseswithincreasingPDMSthickness,resultinginsecondarynp-Aumorphologyeffects,includingareductioninmacroscopiccrack-to-crackdistance,anincreaseinmicroscopiccrackcovere,andawideningofthemicroscopiccracks.However,changesintheligament/porewidthswithPDMSthicknessarenegligible,allowingforindependentoptimizationforcracking.Weexpecttheseresultstoinformtheintegrationoffunctionalnp-Aufilmsoncompliantsubstratesintoemergingapplications,includingflexibleelectronics.Fullarticle(ThisarticlebelongstotheSpecialIssueDesign,FabricationandApplicationsofNanoporousMaterials)9658;9660;ShowFiguresGraphicalabstractFigure1---Figure2---Figure3---Figure4---Figure5---Figure6---Figure7---Figure8---Figure9---Figure10---Figure1111pes,516KiB OpenAccessArticleRadiologicalComparisonofCanalFillbetweenCollaredandNon-CollaredFemoralStems:ATwo-YearFollow-UpafterTotalHipArthroplastybyItayAshkenazi,AmitBenady,ShlomiBenZaken,ShaiFactor,MohamedAbadi,IttaiShichman,SamuelMorgan,iramGold,NimrodSnirandYanivWarschawskiJ.Iming2024,10(5),99;doi.org/10.3390/jiming(registering DOI)-25Apr2024AbstractIntroduction:Collaredfemoralstemsintotalhiparthroplasty(THA)offerreducedsubsidenceandperiprostheticfracturesbutraiseconcernsaboutfitaccuracyandstemsizing.Thisstudycomparescollaredandnon-collaredstemstoassessthestem–canalfillratio(CFR)andfixationindicators,aimingto[...]Readmore.Introduction:Collaredfemoralstemsintotalhiparthroplasty(THA)offerreducedsubsidenceandperiprostheticfracturesbutraiseconcernsaboutfitaccuracyandstemsizing.Thisstudycomparescollaredandnon-collaredstemstoassessthestem–canalfillratio(CFR)andfixationindicators,aimingtoguideimplantselectionandenhanceTHAoutcomes.Methods:Thisretrospectivesingle-centerstudyexaminedprimaryTHApatientswhoreceivedCorailcementlessstemsbetweenAugust2015andOctober2020,withaminimumoftwoyearsofradiologicalfollow-up.Thestudycomparedpreoperativebonequalityassessments,includingtheDorrclassification,thecanalflareindex(CFI),themorphologicalcorticalindex(MCI),andthecanalboneratio(CBR),aswellaspostoperativeradiographicevaluations,suchastheCFRandcomponentfixation,betweenpatientswhoreceivedacollaredoranon-collaredfemoralstem.Results:Thestudyanalyzed202THAs,with103inthecollaredcohortand99inthenon-collaredcohort.Patients’demographicsshoweddifferencesine(p=0.02)andASAclassification(p=0.01)butsimilarpreoperativebonequalitybetweengroups,assuggestedbytheDorrclassification(p=0.15),CFI(p=0.12),MCI(p=0.26),andCBR(p=0.50).Atthetwo-yearfollow-up,femoralstemCFRs(p=0.59andp=0.27)werecomparablebetweencollaredandnon-collaredcohorts.Subsidencerateswerealmostdoubledfornon-collaredpatients(19.2vs.11.7%,p=0.17),however,nottoalevelofclinicalsignificance.Conclusion:Thefindingsofthisstudyshowthatbothcollaredandnon-collaredCorailstemsproducecomparableoutcomesintermsoftheCFRandradiographicindicatorsforstemfixation.Thesefindingsreduceconcernsaboutstemunder-sizingandmicro-motionincollaredstems.WhilethisstudyprovidesinsightsintothecollardesigndebateinTHA,furtherresearchremainsnecessary.Fullarticle(ThisarticlebelongstotheSectionMedicalIming)MoreArticles...OpenAccessJournalsAcousticsActaMicrobiologicaHellenica(AMH)ActuatorsAdministrativeSciencesAdolescentsAdvancesinRespiratoryMedicine(ARM)AerobiologyAerospacericultureriEngineeringrochemicalsronomyAIAirAlgorithmsAllergiesAlloysAnalyticaAnalyticsAnatomiaAnesthesiaResearchAnimalsAntibioticsAntibodiesAntioxidantsAppliedBiosciencesAppliedMechanicsAppliedMicrobiologyAppliedNanoAppliedSciencesAppliedSystemInnovation(ASI)AppliedChemAppliedMathAquacultureJournalArchitectureArthropodaArtsAstronomyAtmosphereAtomsAudiologyResearchAutomationAxiomsBacteriaBatteriesBehioralSciencesBeveresBigDataandCognitiveComputing(BDCC)BioChemBioengineeringBiologicsBiologyBiologyandLifeSciencesForumBiomassBiomechanicsBioMedBiomedicinesBioMedInformaticsBiomimeticsBiomoleculesBiophysicaBiosensorsBioTechBirdsBlockchainsBrainSciencesBuildingsBusinessesCCancersCardiogeneticsCatalystsCellsCeramicsChallengesChemEngineeringChemistryChemistryProceedingsChemosensorsChildrenChipsCivilEngCleanTechnologies(CleanTechnol.)ClimateClinicalandTranslationalNeuroscience(CTN)ClinicsandPracticeClocks&SleepCoastsCoatingsColloidsandInterfacesColorantsCommoditiesComplicationsCompoundsComputationComputerSciences&MathematicsForumComputersCondensedMatterConservationConstructionMaterialsCorrosionandMaterialsDegradation(CMD)CosmeticsCOVIDCropsCryptographyCrystalsCurrentIssuesinMolecularBiology(CIMB)CurrentOncologyDairyDataDentistryJournalDermatoDermatopathologyDesignsDiabetologyDinosticsDieteticsDigitalDisabilitiesDiseasesDiversityDNADronesDrugsandDrugCandidates(DDC)DynamicsEarthEcologiesEconometricsEconomiesEducationSciencesElectricityElectrochemElectronicMaterialsElectronicsEmergencyCareandMedicineEncyclopediaEndocrinesEnergiesEngEngineeringProceedingsEntropyEnvironmentalSciencesProceedingsEnvironmentsEpidemiologiaEpigenomesEuropeanBurnJournal(EBJ)EuropeanJournalofInvestigationinHealth,PsychologyandEducation(EJIHPE)FermentationFibersFinTechFireFishesFluidsFoodsForecastingForensicSciencesForestsFossilStudiesFoundationsFractalandFractional(FractalFract)FuelsFutureFutureInternetFuturePharmacologyFutureTransportationGalaxiesGamesGasesGastroenterologyInsightsGastrointestinalDisordersGastronomyGelsGenealogyGenesGeographiesGeoHazardsGeomaticsGeosciencesGeotechnicsGeriatricsGlaciesGout,Urate,andCrystalDepositionDisease(GUCDD)GrassesHardwareHealthcareHeartsHematoHematologyReportsHeriteHistoriesHorticulturaeHospitalsHumanitiesHumansHydrobiologyHydrogenHydrologyHygieneImmunoInfectiousDiseaseReportsInformaticsInformationInfrastructuresInorganicsInsectsInstrumentsInternationalJournalofEnvironmentalResearchandPublicHealth(IJERPH)InternationalJournalofFinancialStudies(IJFS)InternationalJournalofMolecularSciences(IJMS)InternationalJournalofNeonatalScreening(IJNS)InternationalJournalofPlantBiology(IJPB)InternationalJournalofTopologyInternationalJournalofTranslationalMedicine(IJTM)InternationalJournalofTurbomachinery,PropulsionandPower(IJTPP)InternationalMedicalEducation(IME)InventionsIoTISPRSInternationalJournalofGeo-Information(IJGI)JJournalofeingandLongevity(JAL)JournalofCardiovascularDevelopmentandDisease(JCDD)JournalofClinical&TranslationalOphthalmology(JCTO)JournalofClinicalMedicine(JCM)JournalofCompositesScience(J.Compos.Sci.)JournalofCybersecurityandPrivacy(JCP)JournalofDevelopmentalBiology(JDB)JournalofExperimentalandTheoreticalAnalyses(JETA)JournalofFunctionalBiomaterials(JFB)JournalofFunctionalMorphologyandKinesiology(JFMK)JournalofFungi(JoF)JournalofIming(J.Iming)JournalofIntelligence(J.Intell.)JournalofLowPowerElectronicsandApplications(JLPEA)JournalofManufacturingandMaterialsProcessing(JMMP)JournalofMarineScienceandEngineering(JMSE)JournalofMarketAccess&HealthPolicy(JMAHP)JournalofMolecularPathology(JMP)JournalofNanotheranostics(JNT)JournalofNuclearEngineering(JNE)JournalofOtorhinolaryngology,HearingandBalanceMedicine(JOHBM)JournalofPersonalizedMedicine(JPM)JournalofPharmaceuticalandBioTechIndustry(JPBI)JournalofRespiration(JoR)JournalofRiskandFinancialManement(JRFM)JournalofSensorandActuatorNetworks(JSAN)JournalofTheoreticalandAppliedElectronicCommerceResearch(JTAER)JournalofVascularDiseases(JVD)JournalofXenobiotics(JoX)JournalofZoologicalandBotanicalGardens(JZBG)JournalismandMediaKidneyandDialysisKinasesandPhosphatasesKnowledgeLaboratoriesLandLanguesLawsLifeLimnologicalReviewLipidologyLiquidsLiteratureLiversLogicsLogisticsLubricantsLymphaticsMachineLearningandKnowledgeExtraction(MAKE)MachinesMacromolMnetismMnetochemistryMarineDrugsMaterialsMaterialsProceedingsMathematicalandComputationalApplications(MCA)MathematicsMedicalSciencesMedicalSciencesForumMedicinaMedicinesMembranesMeritsMetabolitesMetalsMeteorologyMethaneMethodsandProtocols(MPs)MetrologyMicroMicrobiologyResearchMicromachinesMicroorganismsMicroplasticsMineralsMiningModellingMolbankMoleculesMultimodalTechnologiesandInteraction(MTI)MusclesNanoenergyAdvancesNanomanufacturingNanomaterialsNDTNetworkNeurogliaNeurologyInternationalNeuroSciNitrogenNon-CodingRNA(ncRNA)NursingReportsNutraceuticalsNutrientsObesitiesOceansOncoOpticsOralOrganicsOrganoidsOsteologyOxygenParasitologiaParticlesPathogensPathophysiologyPediatricReportsPetsPharmaceuticalsPharmaceuticsPharmacoepidemiologyPharmacyPhilosophiesPhotochemPhotonicsPhycologyPhyschemPhysicalSciencesForumPhysicsPhysiologiaPlantsPlasmaPlatformsPollutantsPolymersPolysaccharidesPoultryPowdersProceedingsProcessesProsthesisProteomesPsychiatryInternationalPsychoactivesPsychologyInternationalPublicationsQuantumBeamScience(QuBS)QuantumReportsQuaternaryRadiationReactionsRealEstateReceptorsRecyclingReligionsRemoteSensingReportsReproductiveMedicine(Reprod.Med.)ResourcesRheumatoRisksRoboticsRuminantsSafetySciScientiaPharmaceutica(Sci.Pharm.)SclerosisSeedsSensorsSeparationsSexesSignalsSinusitisSmartCitiesSocialSciencesSociétéInternationaled’UrologieJournal(SIUJ)SocietiesSoftwareSoilSystemsSolarSolidsSpectroscopyJournalSportsStandardsStatsStressesSurfacesSurgeriesSurgicalTechniquesDevelopmentSustainabilitySustainableChemistrySymmetrySynBioSystemsTargetsTaxonomyTechnologiesTelecomTextilesThalassemiaReportsThermoTimeandSpaceTomographyTourismandHospitalityToxicsToxinsTransplantologyTraumaCareTrendsinHigherEducationTropicalMedicineandInfectiousDisease(TropicalMed)UniverseUrbanScienceUroVaccinesVehiclesVenereologyVeterinarySciencesVibrationVirtualWorldsVirusesVisionWasteWaterWindWomenWorldWorldElectricVehicleJournal(WEVJ)YouthZoonoticDiseases9658;9660;BrowsebyIndexingScopusWebofScienceSCIESSCIAHCIESCIPubMedMEDLINEPMCEmbaseEiCompendexInspecCAPlus/SciFinder9658;9660;BrowsebySubjectBiology&LifeSciencesBusiness&EconomicsChemistry&MaterialsScienceComputerScience&MathematicsEngineeringEnvironmental&EarthSciencesMedicine&PharmacologyPhysicalSciencesPublicHealth&HealthcareSocialSciences,ArtsandHumanities9658;9660;SelectedJournalsIJMSIMPACTFACTOR5.6AppliedSciencesIMPACTFACTOR2.7SustainabilityIMPACTFACTOR3.9SensorsIMPACTFACTOR3.9JCMIMPACTFACTOR3.9EnergiesIMPACTFACTOR3.2MoleculesIMPACTFACTOR4.6MaterialsIMPACTFACTOR3.4RemoteSensingIMPACTFACTOR5.0CancersIMPACTFACTOR5.2ElectronicsIMPACTFACTOR2.9MathematicsIMPACTFACTOR2.4FoodsIMPACTFACTOR5.2BuildingsIMPACTFACTOR3.8PlantsIMPACTFACTOR4.5NutrientsIMPACTFACTOR5.9AnimalsIMPACTFACTOR3.0PolymersIMPACTFACTOR5.0WaterIMPACTFACTOR3.4DinosticsIMPACTFACTOR3.6BiomedicinesIMPACTFACTOR4.7ronomyIMPACTFACTOR3.7MicroorganismsIMPACTFACTOR4.5ProcessesIMPACTFACTOR3.5HealthcareIMPACTFACTOR2.8ForestsIMPACTFACTOR2.9CellsIMPACTFACTOR6.0JMSEIMPACTFACTOR2.9MedicinaIMPACTFACTOR2.6VirusesIMPACTFACTOR4.7ricultureIMPACTFACTOR3.6NanomaterialsIMPACTFACTOR5.3IJERPHLandIMPACTFACTOR3.9PharmaceuticsIMPACTFACTOR5.4PharmaceuticalsIMPACTFACTOR4.6ReligionsIMPACTFACTOR0.8BiomoleculesIMPACTFACTOR5.5LifeIMPACTFACTOR3.2MicromachinesIMPACTFACTOR3.4AtmosphereIMPACTFACTOR2.9AntioxidantsIMPACTFACTOR7.0GenesIMPACTFACTOR3.5MetalsIMPACTFACTOR2.9SymmetryIMPACTFACTOR2.7ChildrenIMPACTFACTOR2.4CoatingsIMPACTFACTOR3.4VaccinesIMPACTFACTOR7.8HorticulturaeIMPACTFACTOR3.1EducationSciencesIMPACTFACTOR3.0MineralsIMPACTFACTOR2.5BrainSciencesIMPACTFACTOR3.3JPMIMPACTFACTOR3.4BioengineeringIMPACTFACTOR4.6ExploreAllJournals...HighlyAccessedArticlesLatestBooksMoreBooksandReprints...News19April2024AnnualReport2023—Released15April2024MeetUsatthe12thWorldBiomaterialsCongress(WBC2024),26–31May2024,Daegu,Korea12April2024Prof.Dr.KatrinScheinemannAppointedSectionE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